{"id":4630,"date":"2026-07-31T07:16:45","date_gmt":"2026-07-31T07:16:45","guid":{"rendered":"https:\/\/peptoscience.com\/?post_type=product&p=4630"},"modified":"2026-07-31T07:16:54","modified_gmt":"2026-07-31T07:16:54","slug":"dapoxetine-60mg","status":"publish","type":"product","link":"https:\/\/peptoscience.com\/it\/product\/dapoxetine-60mg\/","title":{"rendered":"Dapoxetine 60mg"},"content":{"rendered":"

Dapoxetine<\/a> 60mg<\/h1>\n
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Dapoxetine<\/a> (brand names: Priligy, others) is a selective serotonin reuptake inhibitor (SSRI) specifically developed and approved for treating\u00a0premature ejaculation (PE)<\/strong>\u00a0in adult men aged 18-64. The standard dose is\u00a060mg<\/strong>, taken as needed\u00a01-3 hours before anticipated sexual activity<\/strong>. It’s\u00a0not<\/strong>\u00a0for erectile dysfunction (ED) or daily use like other SSRIs (e.g., for depression).<\/p>\n

Key Facts and Evidence<\/h4>\n
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  • Mechanism<\/strong>: It works by increasing serotonin levels in the brain, delaying ejaculation by modulating the ejaculatory reflex. Clinical trials (e.g., phase III studies published in\u00a0The Lancet<\/em>\u00a02006 and\u00a0Journal of Sexual Medicine<\/em>\u00a02009) showed it extends intravaginal ejaculatory latency time (IELT) by 2.5-3x compared to placebo (from ~1 min to ~3-4 min).<\/li>\n
  • Approval<\/strong>: Approved by EMA (Europe, 2009), FDA (not in US but available via import), and in many countries like India, Australia. Not for women or children.<\/li>\n
  • Dosing<\/strong>:<\/li>\n<\/ul>\n<\/div>\n
    \n\n\n\n\n\n\n
    Dose<\/th>\nWhen to Take<\/th>\nMax Frequency<\/th>\n<\/tr>\n<\/thead>\n
    30mg (starting, if needed)<\/td>\n1-3 hrs before sex<\/td>\nOnce per 24 hrs<\/td>\n<\/tr>\n
    60mg (standard)<\/td>\n1-3 hrs before sex<\/td>\nOnce per 24 hrs<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
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    Efficacy Data<\/h4>\n
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    • Meta-analyses (e.g.,\u00a0Urology<\/em>\u00a02019, reviewing 6 RCTs with >6,000 men): 60mg improves PE in 70-80% of men vs. 30-40% placebo. Patient-reported satisfaction increases ~3x.<\/li>\n
    • Best for lifelong or acquired PE with IELT <2 min.<\/li>\n<\/ul>\n

      Side Effects (Common: 10-20% incidence)<\/h4>\n<\/div>\n
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      Common (mild, transient)<\/th>\nSerious (rare, <1%)<\/th>\n<\/tr>\n<\/thead>\n
      Nausea, headache, dizziness, diarrhea<\/td>\nSyncope (fainting), orthostatic hypotension, serotonin syndrome (if combined with other SSRIs)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
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      • Contraindications<\/strong>: Heart disease, liver\/kidney failure, bipolar disorder, concurrent MAOIs\/SSRIs\/thioridazine, moderate-severe alcohol use. Avoid if PE is due to ED or prostatitis.<\/li>\n
      • Interactions<\/strong>: Potentiates with CYP3A4 inhibitors (ketoconazole, ritonavir), alcohol (\u2191dizziness), PDE5 inhibitors (e.g., sildenafil\u2014use caution, monitor BP).<\/li>\n<\/ul>\n

        Usage Tips (Supported by Guidelines)<\/h4>\n
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        • Swallow whole with water; no food restriction but avoid grapefruit.<\/li>\n
        • Not for daily use<\/strong>\u2014half-life ~1.5 hrs, cleared quickly.<\/li>\n
        • Lifestyle: Combine with behavioral therapy (e.g., stop-start technique) for better results (BJU International<\/em>\u00a02014).<\/li>\n
        • Overdose<\/strong>: >240mg risky; seek ER for nausea\/vomiting\/seizures.<\/li>\n<\/ul>\n

          Important<\/strong>: This is general info from sources like EMA\/FDA labels, PubMed reviews (e.g., PMID 19453821).\u00a0I’m not a doctor\u2014consult a physician for personalized advice, prescription, and screening (e.g., for heart risks). Self-medication can be dangerous.<\/strong>\u00a0Available OTC in some places but requires medical oversight. If buying online, verify legitimacy to avoid counterfeits.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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          Dapoxetine 60mg Dapoxetine (brand names: Priligy, others) is a selective serotonin reuptake inhibitor (SSRI) specifically developed and approved for treating\u00a0premature ejaculation (PE)\u00a0in adult men aged…<\/p>","protected":false},"featured_media":4644,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"etheme_brands":[],"product_brand":[],"product_cat":[15],"product_tag":[144],"class_list":["post-4630","product","type-product","status-publish","has-post-thumbnail","product_cat-uncategorized","product_tag-dapoxetine-60mg","first","instock","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/peptoscience.com\/it\/wp-json\/wp\/v2\/product\/4630","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peptoscience.com\/it\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/peptoscience.com\/it\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/peptoscience.com\/it\/wp-json\/wp\/v2\/comments?post=4630"}],"version-history":[{"count":1,"href":"https:\/\/peptoscience.com\/it\/wp-json\/wp\/v2\/product\/4630\/revisions"}],"predecessor-version":[{"id":4645,"href":"https:\/\/peptoscience.com\/it\/wp-json\/wp\/v2\/product\/4630\/revisions\/4645"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/peptoscience.com\/it\/wp-json\/wp\/v2\/media\/4644"}],"wp:attachment":[{"href":"https:\/\/peptoscience.com\/it\/wp-json\/wp\/v2\/media?parent=4630"}],"wp:term":[{"taxonomy":"brand","embeddable":true,"href":"https:\/\/peptoscience.com\/it\/wp-json\/wp\/v2\/etheme_brands?post=4630"},{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/peptoscience.com\/it\/wp-json\/wp\/v2\/product_brand?post=4630"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/peptoscience.com\/it\/wp-json\/wp\/v2\/product_cat?post=4630"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/peptoscience.com\/it\/wp-json\/wp\/v2\/product_tag?post=4630"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}