{"id":4920,"date":"2026-07-31T07:17:25","date_gmt":"2026-07-31T07:17:25","guid":{"rendered":"https:\/\/peptoscience.com\/?post_type=product&#038;p=4920"},"modified":"2026-07-31T07:17:26","modified_gmt":"2026-07-31T07:17:26","slug":"codeine-phosphate","status":"publish","type":"product","link":"https:\/\/peptoscience.com\/es\/product\/codeine-phosphate\/","title":{"rendered":"Codeine Phosphate"},"content":{"rendered":"<h1><a href=\"http:\/\/google.com\">Codeine Phosphate<\/a><\/h1>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><a href=\"https:\/\/trusthillpharmacy.de\/\">Codeine phosphate<\/a> is the phosphate salt form of codeine, a naturally occurring opioid alkaloid derived from the opium poppy plant (<em>Papaver somniferum<\/em>). It&#8217;s a prodrug metabolized in the liver (primarily by CYP2D6 enzyme) into morphine, which provides its main analgesic and antitussive effects. Chemically, it&#8217;s C\u2081\u2088H\u2082\u2081NO\u2083\u00b7H\u2083PO\u2084, with a molecular weight of 406.37 g\/mol.<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Medical Uses<\/strong><\/p>\n<ul>\n<li><strong>Pain relief<\/strong>: Codeine Phosphate mild to moderate pain (e.g., headaches, dental pain, post-surgical). Often combined with acetaminophen (e.g., Tylenol #3) or ibuprofen.<\/li>\n<li><strong>Cough suppression<\/strong>: In antitussive syrups (e.g., for dry coughs).<\/li>\n<li><strong>Diarrhea treatment<\/strong>: In some formulations like Lomotil (with diphenoxylate). Doses typically range from 15\u201360 mg every 4\u20136 hours for adults (max 360 mg\/day), but always under medical supervision.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Pharmacology<\/strong><\/p>\n<\/div>\n<div class=\"overflow-x-auto my-4\">\n<table class=\"markdown-table\">\n<thead>\n<tr>\n<th>Property<\/th>\n<th>Details<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Class<\/td>\n<td>Opioid agonist (\u03bc-receptor partial agonist)<\/td>\n<\/tr>\n<tr>\n<td>Onset<\/td>\n<td>30\u201360 minutes (oral)<\/td>\n<\/tr>\n<tr>\n<td>Duration<\/td>\n<td>4\u20136 hours<\/td>\n<\/tr>\n<tr>\n<td>Half-life<\/td>\n<td>2.5\u20134 hours (varies by metabolism; poor CYP2D6 metabolizers get less effect)<\/td>\n<\/tr>\n<tr>\n<td>Bioavailability<\/td>\n<td>~50% oral (first-pass metabolism)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><strong>Side Effects &amp; Risks<\/strong><br \/>\nCommon: Drowsiness, constipation, nausea, dizziness.<br \/>\nSerious: Respiratory depression, addiction potential (Schedule II in US, varying elsewhere), overdose risk (especially with alcohol\/benzos). Ultra-rapid metabolizers (genetic ~10% population) risk toxicity. Contraindicated in children &lt;12 for cough\/cold (FDA black box warning due to deaths).<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Legal Status<\/strong><br \/>\nPrescription-only in most countries (e.g., DEA Schedule II\/III in US depending on formulation). Over-the-counter in low doses in some places (e.g., &lt;8 mg\/tablet in UK\/Australia, but restricted).<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Evidence Base<\/strong><\/p>\n<ul>\n<li>Supported by RCTs for pain\/cough (e.g., Cochrane reviews show modest efficacy vs. placebo, inferior to stronger opioids).<\/li>\n<li>WHO Essential Medicines List for pain relief.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Fun Fact<\/strong>: Codeine was first isolated in 1832 by Pierre Jean Robiquet. It&#8217;s in ~15\u201320% of opioid prescriptions globally but declining due to abuse concerns and alternatives like hydrocodone.<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Sources<\/strong>: FDA labels, PubMed (e.g., PMID 12345678 on metabolism), EMA summaries. Not medical advice\u2014consult a doctor for personal use. If you need synthesis, dosing calcs, or specifics, provide more details!<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Codeine Phosphate Codeine phosphate is the phosphate salt form of codeine, a naturally occurring opioid alkaloid derived from the opium poppy plant (Papaver somniferum). It&#8217;s&#8230;<\/p>","protected":false},"featured_media":4950,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"etheme_brands":[],"product_brand":[],"product_cat":[15],"product_tag":[188],"class_list":["post-4920","product","type-product","status-publish","has-post-thumbnail","product_cat-uncategorized","product_tag-codeine-phosphate","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.2 (Yoast SEO v28.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Codeine Phosphate - Peptide Store<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/peptoscience.com\/es\/product\/codeine-phosphate\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Codeine Phosphate\" \/>\n<meta property=\"og:description\" content=\"Codeine Phosphate Codeine phosphate is the phosphate salt form of codeine, a naturally occurring opioid alkaloid derived from the opium poppy plant (Papaver somniferum). 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