{"id":5033,"date":"2026-07-31T07:17:37","date_gmt":"2026-07-31T07:17:37","guid":{"rendered":"https:\/\/peptoscience.com\/?post_type=product&p=5033"},"modified":"2026-07-31T07:17:43","modified_gmt":"2026-07-31T07:17:43","slug":"oxydolor-80mg","status":"publish","type":"product","link":"https:\/\/peptoscience.com\/de\/product\/oxydolor-80mg\/","title":{"rendered":"OxyDolor 80mg"},"content":{"rendered":"

OxyDolor<\/a> 80mg<\/h1>\n
\n
\n
\n
\n
\n
\n
\n
\n

OxyDolor<\/a> 80mg appears to be a brand-name formulation of\u00a0oxycodone hydrochloride<\/strong>, a potent opioid analgesic used for managing moderate to severe pain. Here’s a concise breakdown based on pharmacological data and standard medical references (e.g., FDA-approved labeling for equivalent oxycodone products like OxyContin):<\/p>\n

Key Facts<\/h3>\n
    \n
  • Active Ingredient<\/strong>: Oxycodone HCl, 80 mg per tablet (extended-release formulation in most cases).<\/li>\n
  • Mechanism<\/strong>: Mu-opioid receptor agonist; binds to CNS receptors to alter pain perception and emotional response to pain.<\/li>\n
  • Indications<\/strong>:\n
      \n
    • Severe chronic pain requiring around-the-clock opioid therapy (e.g., cancer pain, post-surgical).<\/li>\n
    • Not for acute, mild, or intermittent pain.<\/li>\n<\/ul>\n<\/li>\n
    • Dosage (Adults)<\/strong>:<\/li>\n<\/ul>\n<\/div>\n
      \n\n\n\n\n\n\n
      Patient Type<\/th>\nStarting Dose<\/th>\nTitration<\/th>\n<\/tr>\n<\/thead>\n
      Opioid-na\u00efve<\/td>\n10-20 mg q12h (not 80 mg initially)<\/td>\nIncrease by 25-50% q1-2 days as needed<\/td>\n<\/tr>\n
      Opioid-experienced<\/td>\nIndividualized; max 400 mg\/day<\/td>\nMonitor closely<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
      \n
        \n
      • Swallow whole; do not crush\/chew (risks fatal overdose via rapid release).<\/li>\n
      • Pharmacokinetics<\/strong>:<\/li>\n<\/ul>\n<\/div>\n
        \n\n\n\n\n\n\n\n\n
        Parameter<\/th>\nValue<\/th>\n<\/tr>\n<\/thead>\n
        Bioavailability<\/td>\n~60-87%<\/td>\n<\/tr>\n
        T_max (peak plasma)<\/td>\n3-4 hours (ER)<\/td>\n<\/tr>\n
        Half-life<\/td>\n4.5 hours<\/td>\n<\/tr>\n
        Duration<\/td>\n12 hours (ER)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
        \n

        Risks & Warnings (Evidence-Based)<\/h3>\n
          \n
        • High Abuse Potential<\/strong>: Schedule II controlled substance. Extended-release form is crush-resistant in some brands to deter misuse, but diversion remains common (per CDC data: oxycodone involved in ~15% of US opioid overdoses).<\/li>\n
        • Overdose Signs<\/strong>: Respiratory depression, pinpoint pupils, coma. Naloxone reverses (per NIH guidelines).<\/li>\n
        • Contraindications<\/strong>: Acute asthma, paralytic ileus, severe respiratory depression, concurrent MAOIs.<\/li>\n
        • Black Box Warnings<\/strong>\u00a0(FDA):\n
            \n
          • Addiction, abuse, misuse \u2192 life-threatening respiratory depression.<\/li>\n
          • Neonatal opioid withdrawal if used in pregnancy.<\/li>\n
          • Accidental exposure risk (esp. kids).<\/li>\n<\/ul>\n<\/li>\n
          • Side Effects<\/strong>\u00a0(Common, >10% incidence):<\/li>\n<\/ul>\n<\/div>\n
            \n\n\n\n\n\n
            Frequent<\/th>\nSerious<\/th>\n<\/tr>\n<\/thead>\n
            Constipation, nausea, somnolence, pruritus<\/td>\nHypogonadism, QT prolongation, serotonin syndrome (w\/ SSRIs)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
            \n
              \n
            • Interactions<\/strong>: Potentiated by CYP3A4 inhibitors (e.g., ketoconazole); avoid alcohol\/benzos (respiratory arrest risk).<\/li>\n<\/ul>\n

              Evidence Summary<\/h3>\n
                \n
              • Efficacy: Superior to placebo for chronic pain (Cochrane review: NNT ~2.5 for 30% pain reduction).<\/li>\n
              • Safety: Dose-dependent mortality risk; 80 mg is high-strength (reserved for tolerant patients per ASRA guidelines). CDC reports peak oxycodone prescribing in 2012 correlated with overdose epidemics.<\/li>\n<\/ul>\n

                This is not medical advice\u2014consult a physician for personalized use. Misuse can be fatal.<\/strong>\u00a0For official info, check Drugs.com or FDA labels for OxyContin (closest equivalent). If this is a specific query (e.g., side effects, alternatives), provide more details!<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

                <\/div>\n<\/div>\n<\/div>\n<\/div>\n
                \n
                \n
                \n
                \n
                <\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

                OxyDolor 80mg OxyDolor 80mg appears to be a brand-name formulation of\u00a0oxycodone hydrochloride, a potent opioid analgesic used for managing moderate to severe pain. Here’s a…<\/p>","protected":false},"featured_media":5054,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"etheme_brands":[],"product_brand":[],"product_cat":[66],"product_tag":[207],"class_list":["post-5033","product","type-product","status-publish","has-post-thumbnail","product_cat-painkillers","product_tag-oxydolor-80mg","first","instock","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product\/5033","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/comments?post=5033"}],"version-history":[{"count":1,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product\/5033\/revisions"}],"predecessor-version":[{"id":5055,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product\/5033\/revisions\/5055"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/media\/5054"}],"wp:attachment":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/media?parent=5033"}],"wp:term":[{"taxonomy":"brand","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/etheme_brands?post=5033"},{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product_brand?post=5033"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product_cat?post=5033"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product_tag?post=5033"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}