{"id":4932,"date":"2026-07-31T07:17:25","date_gmt":"2026-07-31T07:17:25","guid":{"rendered":"https:\/\/peptoscience.com\/?post_type=product&p=4932"},"modified":"2026-07-31T07:17:29","modified_gmt":"2026-07-31T07:17:29","slug":"xenical-120mg","status":"publish","type":"product","link":"https:\/\/peptoscience.com\/de\/product\/xenical-120mg\/","title":{"rendered":"Xenical 120mg"},"content":{"rendered":"

Xenical 120mg<\/a><\/h1>\n
\n
\n
\n
\n
\n
\n
\n
\n

Xenical 120mg<\/a> is a prescription medication containing orlistat 120mg per capsule<\/strong>, primarily used for\u00a0weight management<\/strong>\u00a0in adults who are obese (BMI \u226530 kg\/m\u00b2) or overweight (BMI \u226527 kg\/m\u00b2) with related health risks like hypertension, diabetes, or high cholesterol. It’s not a “magic pill” but works alongside a reduced-calorie diet and exercise.<\/p>\n

How It Works<\/h4>\n
    \n
  • Mechanism<\/strong>: Orlistat is a\u00a0lipase inhibitor<\/strong>. It binds to enzymes in the gut (gastric and pancreatic lipases), preventing the breakdown and absorption of about 25-30% of dietary fats. Unabsorbed fats are excreted in stool.<\/li>\n
  • Evidence<\/strong>: Clinical trials (e.g., 4-year XENDOS study, n=3304) showed ~10% average weight loss over 1 year vs. placebo, with sustained benefits when combined with lifestyle changes. FDA-approved since 1999; also EMA-approved.<\/li>\n<\/ul>\n

    Dosage & Administration<\/h4>\n<\/div>\n
    \n\n\n\n\n\n\n\n\n
    Aspect<\/th>\nDetails<\/th>\n<\/tr>\n<\/thead>\n
    Standard Dose<\/td>\n120mg orally,\u00a03 times daily<\/strong>\u00a0with meals containing fat (\u226430% of calories from fat per meal). Skip if meal has no fat.<\/td>\n<\/tr>\n
    Duration<\/td>\nTypically 3-6 months initially; continue if \u22655% weight loss in 12 weeks. Max 2 years studied.<\/td>\n<\/tr>\n
    Missed Dose<\/td>\nSkip; don’t double up.<\/td>\n<\/tr>\n
    Form<\/td>\nHard capsules (turquoise cap\/body).<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
    \n

    Side Effects<\/h4>\n

    Mostly\u00a0gastrointestinal (GI)<\/strong>\u00a0due to fat malabsorption\u2014occur in ~20-30% of users, dose-dependent on dietary fat. | Common (\u226510%) | Oily spotting, flatulence with discharge, fecal urgency, fatty\/oily stool, liquid stool, fecal incontinence, increased defecation. | | Less Common (1-10%) | Abdominal pain, nausea, headache, menstrual changes. | | Rare\/Serious (<1%) | Liver injury (monitor LFTs), kidney stones (oxalate-related), severe allergic reactions. Hypothyroidism risk if iodine-deficient. |<\/p>\n

    Multivitamin required<\/strong>: Take 2+ hours before\/after Xenical (fat-soluble vitamins A, D, E, K depleted).<\/p>\n

    Contraindications & Warnings<\/h4>\n
      \n
    • Do not use if<\/strong>: Chronic malabsorption syndrome, cholestasis, pregnancy\/breastfeeding, known hypersensitivity.<\/li>\n
    • Caution<\/strong>: IBD, renal impairment (monitor oxalate), diabetes (adjust meds as weight loss affects glucose).<\/li>\n
    • Drug Interactions<\/strong>: Reduces absorption of cyclosporine, amiodarone, warfarin, antiepileptics\u2014space doses. Avoid high-fat supplements.<\/li>\n
    • Overdose<\/strong>: No specific antidote; symptomatic treatment (e.g., anti-diarrheals).<\/li>\n<\/ul>\n

      Effectiveness Data<\/h4>\n<\/div>\n
      \n\n\n\n\n\n\n
      Study<\/th>\nWeight Loss (Xenical vs. Placebo)<\/th>\nAdditional Benefits<\/th>\n<\/tr>\n<\/thead>\n
      1-Year Trials (n>10k)<\/td>\n9-10% vs. 5-6%<\/td>\n\u2193 LDL 10%, \u2193 HbA1c 0.5% in diabetics<\/td>\n<\/tr>\n
      4-Year XENDOS<\/td>\n16% risk reduction in diabetes<\/td>\nSustained if compliant<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
      \n

      Availability & Cost<\/h4>\n
        \n
      • Prescription-only<\/strong>\u00a0in most countries (e.g., US, EU, Australia). OTC version (Alli 60mg) exists for milder use.<\/li>\n
      • Generic orlistat available, cheaper (~5+).<\/li>\n<\/ul>\n

        Important<\/strong>: This is general info from sources like FDA label, EMA SPC, and studies (e.g., PubMed).\u00a0Not medical advice<\/strong>\u2014consult a doctor for personalized use, as it requires BMI assessment and monitoring. Side effects can be socially disruptive; adherence is key (~50% dropout rate in trials). If you have specific questions (e.g., interactions), provide more details!<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

        <\/div>\n<\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        \n
        \n
        <\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

        Xenical 120mg Xenical 120mg is a prescription medication containing orlistat 120mg per capsule, primarily used for\u00a0weight management\u00a0in adults who are obese (BMI \u226530 kg\/m\u00b2) or…<\/p>","protected":false},"featured_media":4966,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"etheme_brands":[],"product_brand":[],"product_cat":[56],"product_tag":[195],"class_list":["post-4932","product","type-product","status-publish","has-post-thumbnail","product_cat-weight-loss","product_tag-xenical-120mg","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product\/4932","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/comments?post=4932"}],"version-history":[{"count":1,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product\/4932\/revisions"}],"predecessor-version":[{"id":4967,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product\/4932\/revisions\/4967"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/media\/4966"}],"wp:attachment":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/media?parent=4932"}],"wp:term":[{"taxonomy":"brand","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/etheme_brands?post=4932"},{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product_brand?post=4932"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product_cat?post=4932"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product_tag?post=4932"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}