{"id":4931,"date":"2026-07-31T07:17:25","date_gmt":"2026-07-31T07:17:25","guid":{"rendered":"https:\/\/peptoscience.com\/?post_type=product&p=4931"},"modified":"2026-07-31T07:17:29","modified_gmt":"2026-07-31T07:17:29","slug":"oxandrolone","status":"publish","type":"product","link":"https:\/\/peptoscience.com\/de\/product\/oxandrolone\/","title":{"rendered":"Oxandrolone"},"content":{"rendered":"

Oxandrolone<\/a><\/h1>\n
\n

Oxandrolone<\/a>, commonly known by brand names like\u00a0Anavar<\/strong>\u00a0or\u00a0Oxandrin<\/strong>, is a synthetic anabolic-androgenic steroid (AAS) derived from dihydrotestosterone (DHT). It was first synthesized in the 1960s by Searle Laboratories (now part of Pfizer) and is one of the mildest oral steroids available.<\/p>\n

Key Chemical and Pharmacological Facts<\/h4>\n
    \n
  • Chemical Formula<\/strong>: C\u2081\u2089H\u2083\u2080O\u2083<\/li>\n
  • Molecular Weight<\/strong>: 306.44 g\/mol<\/li>\n
  • Half-Life<\/strong>: 9\u201310 hours (oral form)<\/li>\n
  • Mechanism of Action<\/strong>: Binds to androgen receptors in muscle and bone tissue, promoting protein synthesis, nitrogen retention, and red blood cell production. It has a high anabolic rating (322\u2013630) and low androgenic rating (24), making it less likely to cause masculinizing effects compared to testosterone.<\/li>\n<\/ul>\n

    Evidence<\/strong>: These properties are well-documented in pharmacological studies, such as those in\u00a0Journal of Clinical Endocrinology & Metabolism<\/em>\u00a0(e.g., a 2004 study showing its efficacy in muscle wasting without strong virilization).<\/p>\n

    Approved Medical Uses<\/h4>\n

    Oxandrolone is FDA-approved for:<\/p>\n

      \n
    • Promoting weight gain<\/strong>\u00a0after surgery, chronic infections, or severe trauma.<\/li>\n
    • Offsetting protein catabolism<\/strong>\u00a0in burns or osteoporosis.<\/li>\n
    • Treating growth failure<\/strong>\u00a0in children (e.g., Turner syndrome) due to its minimal impact on growth plates.<\/li>\n
    • Alleviating bone pain<\/strong>\u00a0in osteoporosis.<\/li>\n<\/ul>\n

      Dosing (Medical)<\/strong>: Typically 2.5\u201320 mg\/day for adults, divided doses; lower for children. Always under medical supervision.<\/p>\n

      Evidence<\/strong>: FDA approval since 1964, supported by clinical trials like a 1997 study in\u00a0Annals of Surgery<\/em>\u00a0demonstrating 20\u201340% lean body mass gains in burn patients.<\/p>\n

      Non-Medical\/Performance Use<\/h4>\n

      Bodybuilders and athletes misuse it for:<\/p>\n

        \n
      • Cutting cycles<\/strong>: Preserves muscle during calorie deficits, enhances vascularity, and mildly boosts strength.<\/li>\n
      • Stacks<\/strong>: Often combined with testosterone or Winstrol.<\/li>\n<\/ul>\n

        Typical Abuse Dosing<\/strong>: 20\u201380 mg\/day (men), 5\u201320 mg\/day (women) for 6\u20138 weeks.<\/p>\n

        Evidence<\/strong>: Observational data from\u00a0British Journal of Sports Medicine<\/em>\u00a0(2010s studies) links its popularity to low water retention and hepatotoxicity compared to other orals.<\/p>\n

        Side Effects and Risks<\/h4>\n<\/div>\n
        \n\n\n\n\n\n\n\n\n\n
        Category<\/th>\nCommon Effects<\/th>\nSerious Risks<\/th>\n<\/tr>\n<\/thead>\n
        Liver<\/td>\nMild elevation in enzymes (it’s 17-alpha alkylated, so hepatotoxic)<\/td>\nPeliosis hepatis, tumors (rare at low doses)<\/td>\n<\/tr>\n
        Hormonal<\/td>\nTestosterone suppression, cholesterol imbalance (lowers HDL)<\/td>\nGynecomastia, hair loss, acne (dose-dependent)<\/td>\n<\/tr>\n
        Cardiovascular<\/td>\nBlood pressure increase<\/td>\nAtherosclerosis risk<\/td>\n<\/tr>\n
        Women-Specific<\/td>\nVoice deepening, clitoral enlargement<\/td>\nMenstrual irregularities<\/td>\n<\/tr>\n
        Other<\/td>\nNausea, headaches<\/td>\nDependency with chronic use<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
        \n

        Evidence<\/strong>: A 2018 meta-analysis in\u00a0Steroids<\/em>\u00a0journal reviewed 20+ studies, finding liver toxicity in <5% at <40 mg\/day but rising sharply higher. Long-term use correlates with 2\u20133x cardiovascular risk per WHO data.<\/p>\n

        Legality<\/h4>\n
          \n
        • US<\/strong>: Schedule III controlled substance (prescription-only; illegal without Rx).<\/li>\n
        • UK\/EU<\/strong>: Class C (possession legal, supply illegal).<\/li>\n
        • Sports<\/strong>: Banned by WADA (detectable 3\u20134 weeks post-use).<\/li>\n<\/ul>\n

          Evidence<\/strong>: DEA scheduling since 1990 under Anabolic Steroid Control Act; WADA prohibited list updated annually.<\/p>\n

          Detection and Alternatives<\/h4>\n
            \n
          • Urine Test<\/strong>: Metabolites detectable 3\u20134 weeks.<\/li>\n
          • Legal Alternatives<\/strong>: SARMs like Ostarine (less regulated, similar effects but unapproved for humans) or natural supplements (e.g., creatine, protein).<\/li>\n<\/ul>\n

            Caution<\/strong>: Not for self-medication. Consult a doctor for legitimate needs\u2014bloodwork is essential to monitor lipids\/liver. Misuse can lead to permanent damage.<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

            Oxandrolone Oxandrolone, commonly known by brand names like\u00a0Anavar\u00a0or\u00a0Oxandrin, is a synthetic anabolic-androgenic steroid (AAS) derived from dihydrotestosterone (DHT). It was first synthesized in the 1960s…<\/p>","protected":false},"featured_media":4964,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"etheme_brands":[],"product_brand":[],"product_cat":[56],"product_tag":[194],"class_list":["post-4931","product","type-product","status-publish","has-post-thumbnail","product_cat-weight-loss","product_tag-oxandrolone","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product\/4931","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/comments?post=4931"}],"version-history":[{"count":1,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product\/4931\/revisions"}],"predecessor-version":[{"id":4965,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product\/4931\/revisions\/4965"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/media\/4964"}],"wp:attachment":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/media?parent=4931"}],"wp:term":[{"taxonomy":"brand","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/etheme_brands?post=4931"},{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product_brand?post=4931"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product_cat?post=4931"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product_tag?post=4931"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}