{"id":4671,"date":"2026-07-31T07:16:48","date_gmt":"2026-07-31T07:16:48","guid":{"rendered":"https:\/\/peptoscience.com\/?post_type=product&#038;p=4671"},"modified":"2026-07-31T07:16:59","modified_gmt":"2026-07-31T07:16:59","slug":"longtec-tablets","status":"publish","type":"product","link":"https:\/\/peptoscience.com\/de\/product\/longtec-tablets\/","title":{"rendered":"Longtec Tablets"},"content":{"rendered":"<h1><a href=\"http:\/\/google.com\">Longtec Tablets<\/a><\/h1>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><a href=\"https:\/\/trusthillpharmacy.de\/\">Longtec<\/a> tablets is a brand name for <strong>oxycodone hydrochloride prolonged-release tablets<\/strong>, a strong opioid painkiller. It&#8217;s designed for\u00a0<strong>moderate to severe pain<\/strong>\u00a0that requires long-term management, such as chronic pain from cancer, severe arthritis, or post-surgical recovery. Unlike immediate-release oxycodone (e.g., OxyNorm), Longtec releases the drug slowly over 12 hours, providing extended relief.<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Key Facts<\/strong>\u00a0(based on official UK product information from the Summary of Product Characteristics, SmPC, via medicines.org.uk and EMA data):<\/p>\n<ul>\n<li><strong>Active Ingredient<\/strong>: Oxycodone HCl (equivalent to 5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 60mg, 80mg, or 120mg oxycodone base per tablet).<\/li>\n<li><strong>Manufacturer<\/strong>: Mundipharma (commonly prescribed in the UK, Ireland, and parts of Europe).<\/li>\n<li><strong>Form<\/strong>: Film-coated, prolonged-release tablets (do not crush or chew\u2014doing so can cause overdose).<\/li>\n<li><strong>Dosage<\/strong>: Typically starts at 10mg every 12 hours for opioid-na\u00efve patients; titrated based on pain control. Maximum daily dose is usually 400mg, but varies by patient.<\/li>\n<li><strong>How it Works<\/strong>: Binds to mu-opioid receptors in the brain and spinal cord, altering pain perception.<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Evidence and Effectiveness<\/strong>:<\/p>\n<ul>\n<li>Supported by clinical trials (e.g., WHO analgesic ladder studies and meta-analyses in\u00a0<em>The Lancet<\/em>\u00a0and\u00a0<em>Cochrane Reviews<\/em>). Oxycodone is as effective as morphine for chronic pain, with studies showing ~50-70% pain reduction in responsive patients (e.g., PORTAL trial, 2017).<\/li>\n<li>Superior for some due to less histamine release (fewer itch\/sedation side effects vs. morphine).<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Common Side Effects<\/strong>\u00a0(from SmPC and NHS data):<\/p>\n<\/div>\n<div class=\"overflow-x-auto my-4\">\n<table class=\"markdown-table\">\n<thead>\n<tr>\n<th>Frequency<\/th>\n<th>Side Effects<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Very Common (&gt;10%)<\/td>\n<td>Constipation, drowsiness, nausea, dizziness, headache, itching<\/td>\n<\/tr>\n<tr>\n<td>Common (1-10%)<\/td>\n<td>Vomiting, dry mouth, sweating, confusion, low blood pressure<\/td>\n<\/tr>\n<tr>\n<td>Serious (Rare)<\/td>\n<td>Respiratory depression, addiction, overdose (pinpoint pupils, slow breathing), serotonin syndrome if combined with antidepressants<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"prose break-words dark:prose-invert prose-p:leading-relaxed prose-pre:p-0 fix-max-with-100 prose-p:!mt-0\">\n<p class=\"mb-2 last:mb-0\"><strong>Warnings and Risks<\/strong>:<\/p>\n<ul>\n<li><strong>High Addiction Potential<\/strong>: Schedule 2 controlled drug (UK Misuse of Drugs Act). Risk of dependence with long-term use\u2014NICE guidelines recommend regular review and tapering.<\/li>\n<li><strong>Overdose Risk<\/strong>: Symptoms include coma, respiratory arrest. Naloxone reverses it (per BNF).<\/li>\n<li><strong>Contraindications<\/strong>: Acute respiratory depression, paralytic ileus, severe liver\/kidney issues.<\/li>\n<li><strong>Interactions<\/strong>: Avoid with alcohol, benzodiazepines, MAOIs (increases sedation\/respiratory risk\u2014FDA black box warning equivalent).<\/li>\n<li><strong>Pregnancy\/Breastfeeding<\/strong>: Category C; use only if benefits outweigh risks (neonatal withdrawal possible).<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Usage Guidelines<\/strong>\u00a0(NHS\/BNF Recommendations):<\/p>\n<ol>\n<li>Swallow whole with water, every 12 hours.<\/li>\n<li>Do not stop abruptly\u2014taper to avoid withdrawal (flu-like symptoms, anxiety).<\/li>\n<li>Monitor for tolerance (needing higher doses).<\/li>\n<\/ol>\n<p class=\"mb-2 last:mb-0\"><strong>Availability<\/strong>: Prescription-only. Not over-the-counter. In the UK, costs ~\u00a31-5 per tablet via NHS (generic oxycodone cheaper).<\/p>\n<p class=\"mb-2 last:mb-0\"><strong>Sources<\/strong>:<\/p>\n<ul>\n<li><a>electronic Medicines Compendium (emc) &#8211; Longtec SmPC<\/a><\/li>\n<li>British National Formulary (BNF), NICE guidelines on opioids.<\/li>\n<li>PubMed studies (e.g., &#8220;Oxycodone for cancer pain&#8221; meta-analysis, 2020).<\/li>\n<\/ul>\n<p class=\"mb-2 last:mb-0\"><strong>Important<\/strong>: This is general information,\u00a0<strong>not medical advice<\/strong>. Consult a doctor or pharmacist for personalized guidance, especially if you have health conditions or take other meds. If you&#8217;re experiencing pain or side effects, seek professional help immediately. For emergencies (e.g., overdose), call 999 (UK) or equivalent.<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Longtec Tablets Longtec tablets is a brand name for oxycodone hydrochloride prolonged-release tablets, a strong opioid painkiller. It&#8217;s designed for\u00a0moderate to severe pain\u00a0that requires long-term&#8230;<\/p>","protected":false},"featured_media":4687,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"etheme_brands":[],"product_brand":[],"product_cat":[62],"product_tag":[150],"class_list":["post-4671","product","type-product","status-publish","has-post-thumbnail","product_cat-pain-relief","product_tag-longtec-tablets","first","instock","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product\/4671","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/comments?post=4671"}],"version-history":[{"count":1,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product\/4671\/revisions"}],"predecessor-version":[{"id":4688,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product\/4671\/revisions\/4688"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/media\/4687"}],"wp:attachment":[{"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/media?parent=4671"}],"wp:term":[{"taxonomy":"brand","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/etheme_brands?post=4671"},{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product_brand?post=4671"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product_cat?post=4671"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/peptoscience.com\/de\/wp-json\/wp\/v2\/product_tag?post=4671"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}